Arizona Governor Janet Napolitano is tipped to be homeland security chief, Democratic sources said.
Penny Pritzker, who chaired the finance team for Mr Obama's presidential campaign, could be commerce secretary.
And Bill Clinton has reportedly agreed to vetting of his affairs ahead of his wife becoming secretary of state.
Mr Obama's transition team has confirmed a number of other key advisers and top administration posts, while sources have been discussing the unconfirmed appointments.
Hillary Clinton, Mr Obama's defeated rival for the Democratic presidential nomination, is reported to be considering the secretary of state job, sources have said.
According to Reuters, former President Clinton has offered to allow an ethics review of future business and charitable activities to eliminate any conflict of interest if his wife accepts the se
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